University of Utah Health Care joined pulmonary hypertension patients of all ages to celebrate becoming accredited by the Pulmonary Hypertension Association (PHA)’s accreditation program for Pulmonary Hypertension Care Centers. ... Read More
Investigators at the University of Utah have identified distinct differences in the hearts of advanced heart failure patients who have defied the odds and showed signs of recovery from the disease. Published online in the journal Circulation, the new findings could help clinicians identify the best candidates for cardiac recovery therapies.... Read More
Can a failing heart recover? For many years, the answer to that question was unequivocally “No.” But as the University of Utah School of Medicine’s annual Utah Cardiac Recovery Symposium (U-CARS) will explore on Jan. 12-13, advances in treating heart failure are giving physicians, surgeons and researchers reason to hope the deadly disease might one day be defeated.
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A mother who died unexpectedly, a chance encounter with a snail biologist, a patient whose hands were so swollen that she could barely take care of her newborn. Inspiration often comes from unexpected places, a theme that reverberated throughout University of Utah Health Science’s annual Vitae. This year’s event spotlighted six star junior faculty who captivated the crowd with stories of their science, and how they got to where they are today.... Read More
A factor found in umbilical cord blood could become the basis for developing a new therapy to fight harmful inflammation, University of Utah School of Medicine researchers report. When given to mice, the newly discovered factor countered signs of inflammation and sepsis, such as fever, fluctuations in respiratory rate, and death. The factor circulates in the blood of newborns for about two weeks after birth and is not found in older babies or adults, according to the study published online Sept. 6, 2016, in The Journal of Clinical Investigation.
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Squirting a simple saline solution into the nose twice a day could alleviate chronic nosebleeds just as effectively as spraying with any one of three different medications, reports a study published in JAMA and led by Kevin Whitehead, M.D., F.A.H.A., associate professor of internal medicine at the University of Utah School of Medicine and director of the Utah HHT Clinical Center.... Read More
Research led by Amnon Schlegel, M.D., Ph.D., Assistant Professor of Internal Medicine at the University of Utah School of Medicine and an Investigator with the University of Utah Molecular Medicine Program, reveals that defects in how the liver metabolizes glucose, caused by changes in the abundance of the FOXN3 protein, can also trigger increased blood sugar levels, and may explain why some individuals with a variation in the FOXN3 gene show signs of being at risk for diabetes.... Read More
Adults with hypertension who are age 75 years and older, including those who are frail and with poor overall health, could benefit from lowering their blood pressure below current medical guidelines. The multi-institutional investigation was published online in The Journal of the American Medical Association (JAMA) and presented at the American Geriatrics Society Annual Scientific Meeting on May 19. ... Read More
In a finding that could lead to better treatment of smoking-related lung diseases, scientists are reporting that about half of current or former smokers with normal lung function have respiratory symptoms similar to COPD and an increased risk for exacerbations or “flare ups” of their symptoms despite a lack of COPD diagnosis. Many of these individuals show COPD-like symptoms, such as shortness of breath and difficulty exercising. Researchers note they also have a high rate of respiratory medication use despite a lack of data from clinical trials about appropriate treatment of this particular patient population. ... Read More
One of the most delightful and important responsibilities of any leader is the recruitment and retention of super stars. This spring, we welcomed a bright star to the University of Utah Health Sciences—an outstanding oncologist and scientist who takes the helm of the School of Medicine’s largest department, Internal Medicine. ... Read More
End-stage heart failure patients treated with stem cells harvested from their own bone marrow experienced 37 percent fewer cardiac events - including deaths and hospital admissions related to heart failure - than a placebo-controlled group, reports a new study. Results from ixCELL-DCM, the largest cell therapy trial for treating heart failure to date, will be presented at the 2016 American College of Cardiology Scientific Session and published online in The Lancet on April 4.... Read More
Inheriting a mutation in the APC gene leads to a nearly 100% lifetime risk of colorectal cancer. While colon cancer can be kept at bay by removing the large intestine, these patients also have up to a 15% risk of getting cancer in the small intestine, which is the leading cause of cancer death in this patient group. A new study published in the Journal of the American Medical Association (JAMA), has identified the first prevention treatment for these patients, a two-drug combination that significantly reduces the number and size of precancerous polyps in the small intestine. ... Read More
University of Utah School of Medicine researchers have unexpectedly found that a drug that has been used for the past 50 years to treat heart failure and high blood pressure also inhibits infection by the Epstein Barr virus, which causes mono and is associated with several cancers.
The finding has broad implications: with modification, the drug could be used to treat other illness caused by this class of virus including shingles, mono, and herpes. ... Read More
About eight percent of our DNA is viral in origin: remnants of ancient battles between infectious viruses and our ancestors. A new study published in Science by scientists at the University of Utah School of Medicine shows that evolution has repurposed some of these viral remains into weapons against its own kind. They find that bits of viral DNA embedded in our genome are regulating genes that are integral to our innate immune system.... Read More
A University of Utah-led initiative to help people with rare and untreatable diseases was highlighted by the White House at the Precision Medicine Initiative Summit today. Patient Empowered Precision Medicine Alliance (PEPMA) will lay the groundwork for a pipeline that rapidly matches patients with rare diseases that are untreatable with current therapies to the right drugs for their condition, at a relatively low cost.... Read More
On Jan. 14-15, the University of Utah School of Medicine will become the worldwide focus of heart recovery medicine when leading scientists and clinicians from across the globe come to Salt Lake City for the Utah Cardiac Recovery Symposium (U-CARS). Now in its fourth year, the one-of-a-kind conference has been described as a “think tank” where hundreds of cardiologists, surgeons, radiologists, anesthesiologists, ER physicians, nurses, pharmacists, research scientists and more converge to push forward the field of heart recovery. ... Read More
Patients whose blood pressure target was lowered to reach a systolic goal of less than 120 mmHg had their risk for heart attack, heart failure or stroke reduced by 24 percent, and their risk for death lowered by 27 percent. Compared to a systolic blood pressure goal of less than 140 mmHg, aggressive treatment appeared to be as effective for elderly participants as for adults age 50-74, according to results from the Systolic Blood Pressure Intervention Trial (SPRINT) presented at the American Heart Association meeting and published online in the New England Journal of Medicine (NEJM) on Nov. 9. ... Read More